Prison Break
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| Award (↓) | Year | Category | Nominee / Winner | Person |
|---|---|---|---|---|
| Broadcasting & Cable Critics Poll | 2006 | Best New Show (#2) | Voted | |
| Broadcasting & Cable Critics Poll | 2005 | Best Upcoming Show (#5) | Voted | |
| Artios Award | 2006 | Best Casting for a Dramatic Pilot | Winner | John Papsidera; Wendy O'Brien; Claire Simon. |
| Amy Award | 2008 | Wait This Isn't a Dream Sequence (Worst Plot Twist) | Nominee | Sarah is beheaded |
| Amy Award | 2008 | You Bring the Skis, I'll Bring the Shark (Most Deteriorating Show) | Nominee | |
| ALMA Award | 2008 | Outstanding Supporting Actor in a Drama Television Series | Nominee | Amaury Nolasco |
| ALMA Award | 2006 | Outstanding Supporting Actor in a Television Series | Nominee | Amaury Nolasco |
| ALMA Award | 2006 | Outstanding Director of a Television Drama or Comedy | Winner | Jesus Trevino |
