Two and a Half Men
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| Award | Year (↓) | Category | Nominee / Winner | Person |
|---|---|---|---|---|
| Art Directors Guild Award | 2008 | Excellence in Production Design in Television, Multi-Camera Series | Nominee | John S. Shaffner |
| Teen Choice Award | 2008 | Choice TV Show - Comedy | Nominee | |
| People's Choice Award | 2008 | Favorite Male TV Star | Nominee | Charlie Sheen |
| ALMA Award | 2008 | Outstanding Male Performance in a Comedy Television Series | Nominee | Charlie Sheen |
| People's Choice Award | 2008 | Favorite Television Comedy Series | Winner | |
| ASCAP Film & TV Music Award | 2008 | Top Television Series | Winner | Lee Aronsohn; Grant Geissman |
| Young Artist Award | 2008 | Best Performance by a Leading Young Actor in a Television Comedy or Drama Series | Nominee | Angus T. Jones |
| Emmy Award | 2008 | Outstanding Sound Mixing for a Half-Hour Series or Animated Program | Nominee | Bruce Peters; Kathy Oldham; Charlie McDaniel; Bob LaMasney |
| Emmy Award | 2008 | Outstanding Comedy Series | Nominee | |
| Wave Awards | 2008 | Favorite Clipped Comedy Artist | Nominee | Charlie Sheen |
| Emmy Award | 2008 | Outstanding Supporting Actor in a Comedy Series | Nominee | Jon Cryer |
| Emmy Award | 2008 | Outstanding Supporting Actress in a Comedy Series | Nominee | Holland Taylor |
| Emmy Award | 2008 | Outstanding Lead Actor in a Comedy Series | Nominee | Charlie Sheen |
| Emmy Award | 2008 | Outstanding Hairstyling for a Multi-Camera Series or Special | Nominee | Pixie Schwartz; Krista Borrelli; Ralph M. Abalos; Janice Zoladz |
| Emmy Award | 2008 | Outstanding Makeup (Non-Prosthetic) for a Multi-Camera Series or a Special | Nominee | Janice Berridge; Peggy Nichols |
| Teen Choice Award | 2008 | Choice TV Actor - Comedy | Nominee | Charlie Sheen |
| BMI TV Music Award | 2008 | Winner | Chuck Lorre | |
| Emmy Award | 2007 | Outstanding Supporting Actor in a Comedy Series | Nominee | Jon Cryer |
| Emmy Award | 2007 | Outstanding Supporting Actress in a Comedy Series | Nominee | Holland Taylor |
| Art Directors Guild Award | 2007 | Excellence in Production Design in Television, Multi-Camera Series | Nominee | John Shaffner |
| BMI TV Music Award | 2007 | Winner | Chuck Lorre | |
| Emmy Award | 2007 | Outstanding Supporting Actress in a Comedy Series | Nominee | Conchata Ferrell |
| Variety Top 10 | 2007 | 10 Funniest Scenes (#9) | Winner | |
| People's Choice Award | 2007 | Favorite Male TV Star | Nominee | Charlie Sheen |
| Emmy Award | 2007 | Outstanding Lead Actor in a Comedy Series | Nominee | Charlie Sheen |
| People's Choice Award | 2007 | Favorite Television Comedy Series | Winner | |
| Kids Choice Award | 2007 | Favorite TV Actor | Nominee | Charlie Sheen |
| Teen Choice Award | 2007 | Choice TV Actor - Comedy | Winner | Charlie Sheen |
| Emmy Award | 2007 | Outstanding Multi-Camera Picture Editing for a Series | Winner | Joe Bella |
| ASCAP Film & TV Music Award | 2007 | Top Television Series | Winner | Lee Aronsohn; Grant Geissman |
| Emmy Award | 2007 | Outstanding Cinematography for a Multi-Camera Series | Winner | Steven Silver |
| Emmy Award | 2007 | Outstanding Comedy Series | Nominee | |
| Cadet Award | 2006 | Outstanding Supporting Actor in a Comedy Series | Nominee | Jon Cryer |
| Emmy Award | 2006 | Outstanding Lead Actor in a Comedy Series | Nominee | Charlie Sheen |
| People's Choice Award | 2006 | Favorite Male Television Performer | Nominee | Charlie Sheen |
| Art Directors Guild Award | 2006 | Excellence in Production Design in Television, Multi-Camera Series | Nominee | John Shaffner |
| Cadet Award | 2006 | Outstanding Writing in a Comedy Series | Nominee | Susan Beavers; Don Foster |
| Golden Globe Award | 2006 | Outstanding Actor in a Television Comedy or Musical Series | Nominee | Charlie Sheen |
| Emmy Award | 2006 | Outstanding Multi-Camera Picture Editing for a Series | Winner | Joe Bella |
| Emmy Award | 2006 | Outstanding Multi-Camera Sound Mixing for a Series or Special | Nominee | Bruce Peters, Charlie McDaniel, Kathy Oldham, Bob La Masney |
| Cadet Award | 2006 | Outstanding Ensemble in a Comedy Series | Nominee | |
| ASCAP Film & TV Music Award | 2006 | Top Television Series | Winner | Lee Aronsohn; Grant Geissman |
| BMI TV Music Award | 2006 | Winner | Chuck Lorre | |
| Viewers Voice Award | 2006 | Favorite Half-Hour Show | Winner | |
| Cadet Award | 2006 | Outstanding Guest Actor in a Comedy Series | Nominee | Martin Sheen |
| Viewers Voice Award | 2006 | Favorite Actor in a Comedy Series | Winner | Charlie Sheen |
| Viewers Voice Award | 2006 | Favorite Supporting Actor in a Comedy Series | Winner | Jon Cryer |
| Emmy Award | 2006 | Outstanding Cinematography for a Multi-Camera Series | Nominee | Steven V. Silver |
| Golden Laurel Award | 2006 | Danny Thomas Producer of the Year for Episodic Comedy Television | Nominee | |
| Emmy Award | 2006 | Outstanding Comedy Series | Nominee |
