Plot Synopsis

ME, MYSELF & I is a half-hour comedy series about the defining moments in one man's life over three distinct periods -- as a 14-year-old in 1991, at age 40 in present day and at age 65 in 2042. As a 14-year-old boy living in Chicago in 1991, Alex was on top of the world, inventing cool things and celebrating the Bulls' first championship, until his mom, Maggie, moved them to Los Angeles, the heart of Lakers country, and married a pilot, Ron. With his new stepbrother, Justin, Alex needed to reinvent himself in a new school, where he meets his dream girl, Nori Sterling. In 2017, 40-year-old Alex is an inventor/entrepreneur on top of the world until his wife leaves him and threatens to take their daughter, Abby, with her, sending him into a tailspin that requires the help of his best friend and business partner, Darryl, to get him back on track. In 2042 at 65, Alex is a highly successful businessman who, after suffering a minor heart attack, decides he's ready to reinvent himself once again. Alex announces he's retiring to his adult daughter, Abby, now the general manager of the Chicago Bulls, and he gets a surprise chance to reconnect with his childhood crush, Nori, who now goes by Eleanor. During these three pivotal periods, Alex always manages to find a way to move forward, handling key moments with determination, emotion and humor. After an eight-month break, ME, MYSELF & I returned with new episodes on Saturday, July 7, 2018 from 8-9pm ET/PT, as CBS debuted back-to-back new episodes.
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CBS premiered the series finale of ME, MYSELF & I on Saturday, July 21, 2018 from 8-9:30pm ET/PT, debuting three back-to-back new episodes:

"Phil Ricozzi" (8pm): Mid-life Alex sells one of his inventions to his childhood arch-nemesis, Phil (guest star Stephen Rannazzisi). Also, Young Alex is challenged to a fight by his classmate, Phil (uest star Justin Stella), and Older Alex accompanies Eleanor to Phil's funeral and gives an eulogy when no one steps up to speak.

"The Break Up" (8:30pm): Darryl asks Mid-life Alex to wait until after Wendy's birthday to break up with Lisa. Also, Young Alex runs for student council president against Nori, and Older Alex gets upset when he finds out Abby quit her job.

"There She Goes" (9pm): Mid-life Alex contemplates getting back together with his ex-wife, Sarah (guest star Allison Tolman), when she visits for Abby's birthday party. Also, Young Alex attempts to move on from his crush on Nori by inviting his lab partner, Julia (guest star Cree Cicchino), to the dance, and Older Alex makes one last-ditch effort to keep Eleanor from leaving Los Angeles with her fiance.