Malcolm in the Middle
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| Award (↓) | Year | Category | Nominee / Winner | Person |
|---|---|---|---|---|
| RATTY Award | 2000 | Best Ensemble in a Comedy Series | Nominee | |
| RATTY Award | 2000 | Best Lead Actor in a Comedy Series | Winner | Frankie Muniz |
| RATTY Award | 2000 | Best Supporting Actor in a Comedy Series | Nominee | Bryan Cranston |
| RATTY Award | 2000 | Best Supporting Actress in a Comedy Series | Winner | Jane Kaczmarek |
| RATTY Award | 2000 | Best Guest Actor in a Comedy Series | Nominee | Craig Lamar Traylor |
| RATTY Award | 2000 | Best Guest Actress in a Comedy Series | Winner | Beatrice Arthur |
| RATTY Award | 2000 | Best Writing in a Comedy Series | Winner | Linwood Boomer |
| RATTY Award | 2000 | Best Writing in a Comedy Series | Nominee | Michael Glouberman, Andrew Orenstein |
| RATTY Award | 2000 | Best Directing in a Comedy Series | Winner | Todd Holland |
| RATTY Award | 2000 | Best New Series | Nominee | |
| RATTY Award | 2000 | Series with the Most Potential | Winner | |
| PRISM Award | 2002 | Outstanding Television Comedy Series Episode | Winner | |
| Petcabus Award | 2001 | Best Comedy Series | Nominee | |
| Petcabus Award | 2001 | Best Actor in a Comedy Series | Nominee | Frankie Muniz |
| Petcabus Award | 2001 | Best Actress in a Comedy Series | Winner | Jane Kaczmarek |
| Petcabus Award | 2001 | Best Supporting Actor in a Comedy Series | Winner | Bryan Cranston |
| Petcabus Award | 2000 | Best Comedy Series | Nominee | |
| Petcabus Award | 2000 | Best Actor in a Comedy Series | Nominee | Frankie Muniz |
| Petcabus Award | 2000 | Best Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Petcabus Award | 2000 | Best Supporting Actor in a Comedy Series | Nominee | Bryan Cranston |
| Petcabus Award | 2000 | Best Guest Actor or Actress in a Comedy or Drama Series | Nominee | Beatrice Arthur |
| Peabody Award | 2001 | Winner | ||
| Online Television Academy Award | 2005 | Best Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Online Television Academy Award | 2005 | Best Supporting Actor in a Comedy Series | Nominee | Bryan Cranston |
| Online Television Academy Award | 2004 | Best Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Online Television Academy Award | 2004 | Best Supporting Actor in a Comedy Series | Nominee | Bryan Cranston |
| Online Television Academy Award | 2004 | Best Guest Actress in a Comedy Series | Nominee | Cloris Leachman |
| Online Television Academy Award | 2002 | Best Guest Actress in a Comedy Series | Winner | Cloris Leachman |
| Online Television Academy Award | 2002 | Best Direction in a Comedy Series | Nominee | |
| Online Television Academy Award | 2002 | Best Writing in a Comedy Series | Nominee | |
| Online Television Academy Award | 2002 | Best Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Online Television Academy Award | 2002 | Best Supporting Actor in a Comedy Series | Nominee | Bryan Cranston |
| Online Television Academy Award | 2001 | Best Lead Actor in a Comedy Series | Nominee | Frankie Muniz |
| Online Television Academy Award | 2001 | Best Lead Actress in a Comedy Series | Winner | Jane Kaczmarek |
| Online Television Academy Award | 2001 | Best Supporting Actor in a Comedy Series | Nominee | Bryan Cranston |
| Online Television Academy Award | 2001 | Best Ensemble Cast in a Comedy Series | Nominee | |
| Online Television Academy Award | 2001 | Best Guest Actor in a Comedy Series | Nominee | Robert Loggia |
| Online Television Academy Award | 2001 | Best Guest Actress in a Comedy Series | Nominee | Cloris Leachman |
| Online Television Academy Award | 2001 | Best Direction in a Comedy Series | Nominee | |
| Online Television Academy Award | 2001 | Best Writing in a Comedy Series | Nominee | |
| Online Television Academy Award | 2001 | Best Episode in a Comedy Series | Winner | |
| Online Television Academy Award | 2001 | Best Comedy Series | Nominee | |
| Online Television Academy Award | 2000 | Best New Comedy Series | Winner | |
| Online Television Academy Award | 2000 | Best Lead Actor in a Comedy Series | Nominee | Frankie Muniz |
| Online Television Academy Award | 2000 | Best Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Online Television Academy Award | 2000 | Best Actor in a New Comedy Series | Winner | Frankie Muniz |
| Online Television Academy Award | 2000 | Best Actress in a New Comedy Series | Winner | Jane Kaczmarek |
| Online Television Academy Award | 2000 | Best Guest Actress in a Comedy Series | Winner | Beatrice Arthur |
| Online Television Academy Award | 2000 | Best Writing in a Comedy Series | Nominee | |
| Online Television Academy Award | 2000 | Best Theme Music in a New Television Series | Nominee | John Flansburgh, John Linnell |
