Malcolm in the Middle
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| Award (↓) | Year | Category | Nominee / Winner | Person |
|---|---|---|---|---|
| Online Television Academy Award | 2000 | Best Title Sequence in a New Series | Nominee | |
| NAACP Image Award | 2001 | Outstanding Youth Actor or Actress | Nominee | Craig Lamar Traylor |
| MediaVillage TV Fan Award | 2006 | Outstanding Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| MediaVillage TV Fan Award | 2006 | Outstanding Supporting Actor in a Comedy Series | Nominee | Bryan Cranston |
| Kids Choice Award | 2005 | Favorite TV Actor | Nominee | Frankie Muniz |
| Kids Choice Award | 2004 | Favorite TV Actor | Winner | Frankie Muniz |
| Kids Choice Award | 2003 | Favorite TV Actor | Winner | Frankie Muniz |
| Kids Choice Award | 2002 | Favorite TV Actor | Nominee | Frankie Muniz |
| Kids Choice Award | 2001 | Favorite TV Show | Winner | |
| Internet TV Award | 2003 | Favorite Primetime Comedy Series | Nominee | |
| Hollywood Makeup Artist & Hair Stylist Guild Award | 2002 | Best Period Hair Styling in a Television Series | Nominee | Tammy Kusian, Brent Alan Winholt |
| Golden Satellite Award | 2004 | Best Actress in a Television Comedy or Musical Series | Winner | Jane Kaczmarek |
| Golden Satellite Award | 2004 | Best Actor in a Television Comedy or Musical Series | Nominee | Bryan Cranston |
| Golden Satellite Award | 2002 | Best Actress in a Television Comedy or Musical Series | Nominee | Jane Kaczmarek |
| Golden Satellite Award | 2001 | Best Actor in a Television Comedy or Musical Series | Winner | Frankie Muniz |
| Golden Laurel Award | 2004 | Danny Thomas Producer of the Year for Episodic Comedy Television | Nominee | |
| Golden Laurel Award | 2003 | Danny Thomas Producer of the Year for Episodic Comedy Television | Nominee | |
| Golden Laurel Award | 2002 | Danny Thomas Producer of the Year for Episodic Comedy Television | Nominee | |
| Golden Laurel Award | 2001 | Nova Award for Television | Winner | Linwood Boomer |
| Golden Globe Award | 2003 | Outstanding Actress in a Television Comedy or Musical Series | Nominee | Jane Kaczmarek |
| Golden Globe Award | 2003 | Outstanding Supporting Actor in a Television Series, Miniseries or Made-for-TV Movie | Nominee | Bryan Cranston |
| Golden Globe Award | 2002 | Outstanding Actress in a Television Comedy or Musical Series | Nominee | Jane Kaczmarek |
| Golden Globe Award | 2002 | Outstanding Actor in a Television Comedy or Musical Series | Nominee | Frankie Muniz |
| Golden Globe Award | 2001 | Outstanding Television Comedy or Musical Series | Nominee | |
| Golden Globe Award | 2001 | Outstanding Actress in a Television Comedy or Musical Series | Nominee | Jane Kaczmarek |
| Golden Globe Award | 2001 | Outstanding Actor in a Television Comedy or Musical Series | Nominee | Frankie Muniz |
| Golden Eddie Award | 2002 | Best Edited Half-Hour Television Series | Nominee | Barry Gold |
| Golden Eddie Award | 2001 | Best Edited Half-Hour Television Series | Winner | Nancy Morrison |
| Future Classic Award | 2001 | Winner | ||
| futoncritic's Best Eps | 2002 | 50 Best Eps of 2001 (#35) | Winner | |
| futoncritic's Best Eps | 2002 | 50 Best Eps of 2001 (#16) | Winner | |
| Family Television Award | 2001 | Television Comedy Series | Winner | |
| Family Television Award | 2001 | Television Actress | Winner | Jane Kaczmarek |
| EW's All Time Greatest/Worst Lists | 2008 | 100 New TV Classics (#88) | Winner | |
| Environmental Media Association Award | 2003 | Turner Prize | Nominee | |
| Emmy Award | 2006 | Outstanding Guest Actress in a Comedy Series | Winner | Cloris Leachman |
| Emmy Award | 2006 | Outstanding Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Emmy Award | 2006 | Outstanding Choreography | Nominee | Fred Tallaksen |
| Emmy Award | 2006 | Outstanding Supporting Actor in a Comedy Series | Nominee | Bryan Cranston |
| Emmy Award | 2005 | Outstanding Music and Lyrics | Nominee | Charles Sydnor; Eric Kaplan |
| Emmy Award | 2005 | Outstanding Guest Actress in a Comedy Series | Nominee | Cloris Leachman |
| Emmy Award | 2005 | Outstanding Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Emmy Award | 2004 | Outstanding Choreography | Nominee | Fred Tallekson |
| Emmy Award | 2004 | Outstanding Guest Actress in a Comedy Series | Nominee | Cloris Leachman |
| Emmy Award | 2004 | Outstanding Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Emmy Award | 2003 | Outstanding Single-Camera Picture Editing for a Comedy Series | Winner | Mark Scheib, Steve Welch |
| Emmy Award | 2003 | Outstanding Lead Actress in a Comedy Series | Nominee | Jane Kaczmarek |
| Emmy Award | 2003 | Outstanding Supporting Actor in a Comedy Series | Nominee | Bryan Cranston |
| Emmy Award | 2003 | Outstanding Guest Actress in a Comedy Series | Nominee | Cloris Leachman |
| Emmy Award | 2002 | Outstanding Stunt Coordination | Nominee |
